About Omega6:Omega3 ratio

So, the logic behind the o6:o3 ratio theory is that both compete for the same enzymes, so having too much o6 is detrimental to your o3 intake. But, wouldn't it make more sense to say: "don't eat too much o6 *in the same meal* you eat your o3's"? I'm assuming that, for example, a breakfast that contains almost exclusively o3's and no o6's, no matter what you eat throughout the rest of the day, nothing will interfere with the o3's you got from breakfast. Does this make any sense, or am i missing something? Maybe i don't understand how enzymes work, and whether they act immediately or not. Thanks.

Answer

I think the idea that you should limit your n6 PUFA intake is a bit outdated, and there is a larger body of evidence to suggest that total PUFA intake (including n6 FAs) improves cardiovascular health. Personally, I wouldn’t focus on this ratio and instead, try to increase your intake of healthy vegetable fats such as nuts, seeds, EVOO, avocado and fatty fish.

This Harvard health article sums it up nicely and includes references: https://www.health.harvard.edu/newsletter_article/no-need-to-avoid-healthy-omega-6-fats

Answer

AFAIK since you store some of the fat you intake (its not all burned for energy) when these are later released to the blood stream via lipolysis then now you have the various fatty acids competing in different functions/enzymes in the ratios they were stored in (roughly speaking, some fatty acids may be preferentially stored or metabolized). I think this would be one reason to keep your ratio as desired at all times . The easiest way to do that might then be to just keep n-6 intake low