The number one recommendation to alleviate lipedema is to lose weight. From what I can tell there is limited data to suggest fat cells have shorter apoptosis cycles (programmed cell death), which is what autophagy help trigger. Currently it looks like it will trigger after years of “being inactive”, and this is likely due to it being triglyceride based versus amino acid based (which autophagy mainly goes afterwards).
That being said, fasting in combination with a diet providing low inflammation (for some people it’s low carb, others it’s vegan, for me it’s carnivore) will helpDeplete your fat stores and shrink your fat cells. The lower inflammation helps keep water from filling up those cells ones the fat is used, and helps keep the weight loss going.
Depending on what fasting you have done, I would start with ADF with the fasting day having no calories with exception of a tiny bit of cream in your coffee if you tolerate dairy. More in depth suggestions can be given with a bit more information about what you have done, your other goals, etc.