Piascledine is, as near as I can tell (and I couldn’t find very much clear information, which is a bad sign), all the non-water-soluble parts left over from a soybean or an avocado after you remove the hydrolyzable lipid esters that can be used to make soap (aka saponifiables).
(To even figure that much out, this was my dictionary reference for what the term “unsaponifiables” even means. The standard meaning of that word is just “things that can’t be turned into soap”, but I had to look up what specific biochemical reaction they were talking about, since soapmaking has several biochemical reactions and you could turn anything into soap with enough reactions, so, the details mattered.)
Anyway, its composition is complex, is what I’m saying, which sounds great to certain ears, except that the problem with complex plant extracts is that you can make them even if you have no idea what all is actually in them, just like how you can cook with an avocado without knowing its chemical constituents.
The problem with not knowing what’s in the thing, is that it’s super hard to then use that unknown compound later to take rational steps to increase or decrease any effects it may have (assuming it actually has any effects at all).
So here’s the problem I face: in order to answer your question, about omega-3 fatty acids “helping with absorption” of piascledine, I would first have to know which parts (if any) are active ingredients. I would then need to look up what the pharmacodynamics of those ingredients are, so that we could know whether there are any useful interactions between the biochemistry of omega-3 fatty acids, and the biochemistry of those things.
But I can’t do that.
I can’t do that because piascledine isn’t one ingredient. It’s a hodge podge mixture of lipids, alkyl furans, alkyl triols, aliphatic alkanes, tocopherols, sterols, squalene, and probably a lot more. And in order to truly answer your question, anyone else would have to know these things that I can’t find.
Of course, it’d be easy to just make up an answer, but I think that would be disrespectful if I did that.